Selphyl PRFM Hair Restoration Treatment for Thinning Hair
Noticing more hair in the shower or seeing your part gradually widen can be frustrating, especially when shampoos and topical products are not giving you the improvement you hoped for. For people looking for a treatment that uses components from their own blood, Selphyl PRFM Hair Restoration Treatment for thinning hair offers another option.
Lords & Ladies Salon and Medical Spa provides PRFM hair restoration using a patient’s own platelets and plasma, which are processed and then injected into areas of the scalp where hair is thinning. Treatment plans are customized because hair loss, scalp condition, and individual response can vary considerably.
What Is PRFM Hair Restoration?

PRFM stands for platelet-rich fibrin matrix.
It begins with a small blood draw, much like traditional platelet-rich plasma, or PRP, treatment. The blood is processed in a centrifuge to separate and concentrate platelet-containing plasma. With the SELPHYL® system, that PRP is then converted into PRFM by forming a fibrin matrix around the platelets.
That matrix is what distinguishes PRFM from conventional PRP.
SELPHYL describes the fibrin structure as a scaffold that holds platelets in the treatment area and allows growth factors to be released over a longer period. Manufacturer data indicates that platelet growth-factor release may continue for up to seven days.
For hair restoration, the prepared PRFM is injected into areas of thinning hair on the scalp.
How Is PRFM Different From Traditional PRP?
PRP and PRFM begin in a similar place: your own blood.
Traditional PRP concentrates platelets in plasma and is used in a range of medical and aesthetic applications. PRFM adds another processing step that creates a three-dimensional fibrin matrix.
Think of PRP as delivering concentrated platelets and PRFM as giving those platelets a temporary framework in which to remain.
SELPHYL’s closed preparation system is designed to separate red and white blood cells from the platelet-rich portion before the PRFM is prepared. The company says this process helps create a consistent platelet-rich product while minimizing contamination during preparation.
That does not mean one hair-loss treatment is automatically right for everyone. Your provider should look at the pattern and extent of your thinning before recommending a plan.
How Can PRFM Help With Thinning Hair?
Platelets naturally contain growth factors involved in tissue repair and signaling. Platelet-based treatments have therefore become an area of interest for hair restoration, particularly for people experiencing certain types of progressive thinning.
SELPHYL identifies hair restoration as one of the medical disciplines in which platelet-based therapies are used to support hair growth and hair thickness.
At Lords & Ladies, PRFM is injected directly into the areas where hair is thinning. The goal is to place the patient’s platelet-rich material close to the follicles that are being targeted. Results are not immediate or guaranteed.
Hair grows in cycles, so any response takes time to become visible. Lords & Ladies specifically notes that every PRFM treatment plan is customized and that individual results vary.
Is PRFM Appropriate for Every Type of Hair Loss?
No, and that is one reason a consultation matters.
Hair thinning can have many causes. Genetics are common, but changes in hormones, nutritional deficiencies, medications, illness, scalp conditions, stress, and other factors can also contribute.
A cosmetic hair-restoration treatment should not replace appropriate medical evaluation when the cause of hair loss is unclear.
Sudden shedding, bald patches, scalp inflammation, pain, or rapid unexplained hair loss are particularly good reasons to speak with a healthcare professional before assuming the issue is ordinary age- or genetics-related thinning.
For clients who are appropriate candidates, a Lords & Ladies nurse injector can discuss whether PRFM fits their goals and develop a treatment schedule based on their individual situation.
What Happens During a PRFM Hair Restoration Appointment?
The process begins with a blood draw.
The sample is placed into a centrifuge so the platelet-rich portion can be separated. With the SELPHYL system, the plasma is transferred through a closed system and converted into PRFM before treatment. SELPHYL describes the preparation process itself as relatively quick, with the overall procedure taking about 20 minutes in many applications.
The prepared material is then injected into targeted areas of the scalp.
Because injections are involved, temporary tenderness, redness, swelling, or bruising can occur afterward. SELPHYL notes that mild injection-site irritation and tenderness are possible, while Lords & Ladies also lists temporary redness, swelling, edema, and discomfort among potential post-treatment effects.
How Should You Prepare for PRFM Hair Restoration?
Follow the instructions your provider gives you rather than relying on general online advice.
Lords & Ladies currently advises PRFM hair-restoration clients to arrive well hydrated, eat a light meal beforehand, and avoid caffeine before the appointment. Its published pre-care instructions also discuss temporarily avoiding certain NSAIDs and alcohol because they can affect bleeding or bruising.
However, never stop a prescribed medication simply to prepare for a cosmetic procedure unless the healthcare professional who manages that medication says it is safe to do so.
Make sure your injector knows about your medications, supplements, medical history, and any changes in your health.
What Should You Avoid After Treatment?
Your scalp needs a little time after the injections.
Lords & Ladies’ current PRFM aftercare instructions advise clients not to wash their hair or place direct shower pressure on the scalp for three days. The salon also recommends avoiding strenuous exercise, swimming, direct sunlight, excessive heat, saunas, hot tubs, and head coverings during that initial period. Hair color and other chemical scalp treatments should be avoided for seven days.
These instructions are worth planning around.
If you have a hair-color appointment scheduled the next morning or a weekend at the pool coming up, it may make sense to choose another treatment date.
Learn Whether PRFM Hair Restoration Is Right for You
Hair thinning is personal, and so is the treatment plan. Selphyl PRFM hair restoration treatment for thinning hair uses your own platelet-rich material and SELPHYL’s fibrin-matrix technology to target areas of the scalp where hair is becoming thinner. It may be an option for appropriate candidates, but results vary and the first step should be determining whether PRFM makes sense for your particular pattern of hair loss.
Lords & Ladies Salon and Medical Spa offers complimentary consultations with its certified nurse injectors. Call 1-844-725-6655 or book a consultation with Lords & Ladies to discuss your thinning hair, treatment goals, and whether PRFM hair restoration belongs in your plan.
